Tara Spires: search on Z-Library

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1

Transgenic models of Alzheimer’s disease: Learning from animals

Tara L. Spires, Bradley T. Hyman

Journal:

Neurotherapeutics

Year:

2005

Language:

english

File:

PDF, 290 KB

english, 2005

2

Potassium channels in squid neuron cell bodies: Comparison to axonal channels

Tara Nealey, Sherrill Spires, Ruth Anne Eatock, Ted Begenisich

Journal:

Journal of Membrane Biology

Year:

1993

Language:

english

File:

PDF, 987 KB

english, 1993

3

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo

Fulga, Tudor A., Elson-Schwab, Ilan, Khurana, Vikram, Steinhilb, Michelle L., Spires, Tara L., Hyman, Bradley T., Feany, Mel B.

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 2.80 MB

english, 2006

4

The clinical promise of biomarkers of synapse damage or loss in Alzheimerâs disease

Colom-Cadena, MartÃ, Spires-Jones, Tara, Zetterberg, Henrik, Blennow, Kaj, Caggiano, Anthony, DeKosky, Steven T., Fillit, Howard, Harrison, John E., Schneider, Lon S., Scheltens, Phillip, de Haan, Wi

Journal:

Alzheimer's Research & Therapy

Year:

2020

File:

PDF, 2.04 MB

2020

5

Tau pathophysiology in neurodegeneration: a tangled issue

Tara L. Spires-Jones, William H. Stoothoff, Alix de Calignon, Phillip B. Jones, Bradley T. Hyman

Journal:

Trends in Neurosciences

Year:

2009

Language:

english

File:

PDF, 906 KB

english, 2009

6

The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease

Crimins, Johanna L., Pooler, Amy, Polydoro, Manuela, Luebke, Jennifer I., Spires-Jones, Tara L.

Journal:

Ageing Research Reviews

Year:

2013

Language:

english

File:

PDF, 703 KB

english, 2013

7

Lack of endogenous tau permits tau spreading and protects against tau toxicity in transgenic mice

Wegmann, Susanne, Maury, Eduardo A., Kirk, Molly J., Saqran, Lubna, Roe, Allyson D., Fan, Zhanyun, Nicholls, Samantha B., DeVos, Sarah L., Takeda, Shuko, William, Christopher M., Spires-Jones, Tara L.

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 50 KB

english, 2015

8

Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease

Pickett, Eleanor K., Henstridge, Christopher M., Allison, Elizabeth, Pitstick, Rose, Pooler, Amy, Wegmann, Susanne, Carlson, George, Hyman, Bradley T., Spires-Jones, Tara L.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

9

Caspase activation precedes and leads to tangles

de Calignon, Alix, Fox, Leora M., Pitstick, Rose, Carlson, George A., Bacskai, Brian J., Spires-Jones, Tara L., Hyman, Bradley T.

Journal:

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

10

S2-02-05: Neuritic alterations and dysfunctions in Alzheimer’s disease

Bradley T. Hyman, Tara Spires, Toshifumi Matsui, Jen Orne, Rose Pitstik, George A. Carlson, Karen Ashe

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

11

Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau

McInnes, Joseph, Wierda, Keimpe, Snellinx, An, Bounti, Laura, Wang, Yu-Chun, Stancu, Ilie-Cosmin, Apóstolo, Nuno, Gevaert, Kris, Dewachter, Ilse, Spires-Jones, Tara L., De Strooper, Bart, De Wit, Jori

Journal:

Year:

2018

Language:

english

File:

PDF, 4.07 MB

english, 2018

12

Editorial

Spires-Jones, Tara L

Journal:

Brain Communications

Year:

2020

File:

PDF, 327 KB

2020

13

T cell mediated cerebral hemorrhages and microhemorrhages during passive Aβ immunization in APPPS1 transgenic mice

Melanie Meyer-Luehmann, J Rodrigo Mora, Matthew Mielke, Tara L Spires-Jones, Alix de Calignon, Ulrich H von Andrian, Bradley T Hyman

Journal:

Molecular Neurodegeneration

Year:

2011

Language:

english

File:

PDF, 5.00 MB

english, 2011

14

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

Meyer-Luehmann, Melanie, Spires-Jones, Tara L., Prada, Claudia, Garcia-Alloza, Monica, de Calignon, Alix, Rozkalne, Anete, Koenigsknecht-Talboo, Jessica, Holtzman, David M., Bacskai, Brian J., Hyman,

Journal:

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

15

P1-090: Observation of new senile plaque formation and associated neuritic abnormalities using multiphoton microscopy

Melanie Meyer-Luehmann, Tara L. Spires, Brian J. Bacskai, Bradley T. Hyman

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 62 KB

english, 2006

16

Neurofibrillary tangles remain functionally integrated in cortical networks

Kuchibhotla, Kishore, Wegmann, Susanne, Spires-Jones, Tara, Bacskai, Brian, Hyman, Bradley

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

17

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

Stevenson, Anna J., McCartney, Daniel L., Hillary, Robert F., Redmond, Paul, Taylor, Adele M., Zhang, Qian, McRae, Allan F., Spires-Jones, Tara L., McIntosh, Andrew M., Deary, Ian J., Marioni, Riccard

Journal:

Translational Psychiatry

Year:

2019

File:

PDF, 594 KB

2019

18

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

Will Stoothoff, Phillip B. Jones, Tara L. Spires-Jones, Daniel Joyner, Ekta Chhabra, Kathryn Bercury, Zhanyun Fan, Hong Xie, Brian Bacskai, Jon Edd, Daniel Irimia, Bradley T. Hyman

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 580 KB

english, 2009

19

A transgenic model of the earliest stage of Alzheimer's disease

Bradley T. Hyman, Alix de Calignon, Marc Suarez-Calvet, Christopher William, Rose Pitstick, George A. Carlson, Tara L. Spires-Jones

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

20

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

Tai, Hwan-Ching, Serrano-Pozo, Alberto, Hashimoto, Tadafumi, Frosch, Matthew P., Spires-Jones, Tara L., Hyman, Bradley T.

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 2.12 MB

english, 2012

21

P2-164: In vivo multiphoton imaging of neurofibrillary tangles: Relationship to cell death cascades

de Calignon, Alix, Spires-Jones, Tara, Hyman, Bradley T.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

22

Are Tangles as Toxic as They Look?

Tara L. Spires-Jones, Katherine J. Kopeikina, Robert M. Koffie, Alix de Calignon, Bradley T. Hyman

Journal:

Journal of Molecular Neuroscience

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

23

Monitoring protein aggregation and toxicity in Alzheimer’s disease mouse models using in vivo imaging

Tara L. Spires-Jones, Alix de Calignon, Melanie Meyer-Luehmann, Brian J. Bacskai, Bradley T. Hyman

Journal:

Year:

2011

Language:

english

File:

PDF, 913 KB

english, 2011

24

Pathology of Synapses and Dendritic Spines

Knafo, Shira, Gouras, Gunnar K., Yan, Xiao-Xin, Spires-Jones, Tara

Journal:

Neural Plasticity

Year:

2012

Language:

english

File:

PDF, 44 KB

english, 2012

25

Rapid β-Amyloid Deposition and Cognitive Impairment After Cholinergic Denervation in APP/PS1 Mice

Ramos-Rodriguez, Juan Jose, Pacheco-Herrero, Mar, Thyssen, Diana, Murillo-Carretero, Maria Isabel, Berrocoso, Esther, Spires-Jones, Tara L., Bacskai, Brian J., Garcia-Alloza, Monica

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

26

Complementing Tau: New Data Show that the Complement System Is Involved in Degeneration in Tauopathies

Davies, Caitlin, Spires-Jones, Tara L.

Journal:

Year:

2018

Language:

english

File:

PDF, 651 KB

english, 2018

27

Nanoparticles enhance brain delivery of blood—brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging

Robert M. Koffie, Christian T. Farrar, Laiq-Jan Saidi, Christopher M. William, Bradley T. Hyman and Tara L. Spires-Jones

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

28

Tau pathology does not affect experience-driven single-neuron and network-wide Arc/Arg3.1 responses

Rudinskiy, Nikita, Hawkes, Jonathan M, Wegmann, Susanne, Kuchibhotla, Kishore V, Muzikansky, Alona, Betensky, Rebecca A, Spires-Jones, Tara L, Hyman, Bradley T

Journal:

Acta Neuropathologica Communications

Year:

2014

Language:

english

File:

PDF, 3.18 MB

english, 2014

29

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy

Jones, Phillip B., Rozkalne, Aneta, Meyer-Luehmann, Melanie, Spires-Jones, Tara L., Makarova, Alexandra, Kumar, Anand T. N., Berezovska, Oksana, Bacskai, Brian B., Hyman, Bradley T.

Journal:

Journal of Biomedical Optics

Year:

2008

Language:

english

File:

PDF, 998 KB

english, 2008

30

TAU SPREADING AND TOXICITY

Pickett, Eleanor, Henstridge, Christopher, Jackson, Rosemary J., Herrmann, Abigail G., Wegmann, Susanne, Hyman, Bradley T., Carlson, George A., Spires-Jones, Tara L.

Journal:

Alzheimer's & Dementia

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

31

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Stevenson, Anna J., McCartney, Daniel L., Harris, Sarah E., Taylor, Adele M., Redmond, Paul, Starr, John M., Zhang, Qian, McRae, Allan F., Wray, Naomi R., Spires-Jones, Tara L., McColl, Barry W., McIn

Journal:

Clinical Epigenetics

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

32

P3-434

Spires, Tara L., Meyer-Luehmann, Melanie, Orne, Jennifer D., Backskai, Brian J., Hyman, Bradley T.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 69 KB

english, 2006

33

The Calcium-Binding Protein EFhd2 Modulates Synapse Formation In Vitro and Is Linked to Human Dementia

Borger, Eva, Herrmann, Abigail, Mann, David A., Spires-Jones, Tara, Gunn-Moore, Frank

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2014

Language:

english

File:

PDF, 23.42 MB

english, 2014

34

Modeling Alzheimer’s disease brains in vitro

Henstridge, Christopher M., Spires-Jones, Tara L.

Journal:

Nature Neuroscience

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

35

Non-Invasive RF Technique for Detecting Different Stages of Alzheimerâs Disease and Imaging Beta-Amyloid Plaques and Tau Tangles in the Brain

Saied, Imran, Arslan, Tughrul, Chandran, Siddharthan, Smith, Colin, Spires-Jones, Tara, Pal, Suvankar

Journal:

IEEE Transactions on Medical Imaging

Year:

2020

File:

PDF, 1.20 MB

2020

36

Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain

Tara L. Spires-Jones, Kevin Kay, Roland Matsouka, Anete Rozkalne, Rebecca A. Betensky, Bradley T. Hyman

Journal:

Neuroscience Letters

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

37

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon, Manuela Polydoro, Marc Suárez-Calvet, Christopher William, David H. Adamowicz, Kathy J. Kopeikina, Rose Pitstick, Naruhiko Sahara, Karen H. Ashe, George A. Carlson, Tara L. Spires-Jo

Journal:

Year:

2012

Language:

english

File:

PDF, 4.88 MB

english, 2012

38

Environmental Enrichment Reduces Neuronal Intranuclear Inclusion Load But Has No Effect on Messenger RNA Expression in a Mouse Model of Huntington Disease

Benn, Caroline L., Luthi-Carter, Ruth, Kuhn, Alexandre, Sadri-Vakili, Ghazaleh, Blankson, Kwabena L., Dalai, Sudeb C., Goldstein, Darlene R., Spires, Tara L., Pritchard, Joel, Olson, James M., van Del

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2010

Language:

english

File:

PDF, 1.37 MB

english, 2010

39

Tau Causes Synapse Loss without Disrupting Calcium Homeostasis in the rTg4510 Model of Tauopathy

Kopeikina, Katherine J., Wegmann, Susanne, Pitstick, Rose, Carlson, George A., Bacskai, Brian J., Betensky, Rebecca A., Hyman, Bradley T., Spires-Jones, Tara L., Dickey, Chad A.

Journal:

Year:

2013

Language:

english

File:

PDF, 806 KB

english, 2013

40

P1-486: Decreased neuronal activity in APP transgenic mice measured via dendritic protein synthesis

Meyer-Luehmann, Melanie, Stoothoff, Will, Spires-Jones, Tara L., Kowa, Tomo, Koker, Mirjam, Han, Kelly, Hyman, Bradley T.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

41

Caspase cleavage of tau is critical for oligomeric beta-amyloid–induced sub-lethal apoptotic cascade

Polydoro, Manuela, Hudry, Eloise, Perez-Nievas, Beatriz, Arbel-Ornath, Michal, Sanchez, Laura, Spires-Jones, Tara, Reumers, Veerle, Gómez-Isla, Teresa, Hyman, Bradley

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 67 KB

english, 2013

42

Antidiabetic Polypill Improves Central Pathology and Cognitive Impairment in a Mixed Model of Alzheimer’s Disease and Type 2 Diabetes

Infante-Garcia, Carmen, Ramos-Rodriguez, Juan Jose, Hierro-Bujalance, Carmen, Ortegon, Esperanza, Pickett, Eleanor, Jackson, Rosemary, Hernandez-Pacho, Fernando, Spires-Jones, Tara, Garcia-Alloza, Mon

Journal:

Molecular Neurobiology

Year:

2017

Language:

english

File:

PDF, 7.54 MB

english, 2017

43

Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia

Spires-Jones, Tara L., Fox, Leora M., Rozkalne, Anete, Pitstick, Rose, Carlson, George A., Kazantsev, Aleksey G.

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

44

The Synthesis of Megatubes: New Dimensions in Carbon Materials

Mitchell, Daniel R., Brown, R. Malcolm, Spires, Tara L., Romanovicz, Dwight K., Lagow, Richard J.

Journal:

Inorganic Chemistry

Year:

2001

Language:

english

File:

PDF, 666 KB

english, 2001

45

Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice

Anete Rozkalne, Bradley T. Hyman, Tara L. Spires-Jones

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

46

Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease

Tai, Hwan-Ching, Wang, Bo Y, Serrano–Pozo, Alberto, Frosch, Matthew P, Spires-Jones, Tara L, Hyman, Bradley T

Journal:

Acta Neuropathologica Communications

Year:

2014

Language:

english

File:

PDF, 3.40 MB

english, 2014

47

Soluble tau Species, Not Neurofibrillary Aggregates, Disrupt Neural System Integration in a tau Transgenic Model

Fox, Leora M., William, Christopher M., Adamowicz, David H., Pitstick, Rose, Carlson, George A., Spires-Jones, Tara L., Hyman, Bradley T.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2011

Language:

english

File:

PDF, 3.31 MB

english, 2011

48

TAR-DNA Binding Protein 43 in Pick Disease

Freeman, Stefanie H., Spires-Jones, Tara, Hyman, Bradley T., Growdon, John H., Frosch, Matthew P.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2008

Language:

english

File:

PDF, 628 KB

english, 2008

49

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

Tara L. Spires-Jones, Matthew L. Mielke, Anete Rozkalne, Melanie Meyer-Luehmann, Alix de Calignon, Brian J. Bacskai, Dale Schenk, Bradley T. Hyman

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 745 KB

english, 2009

50

Activation de caspases et formation de dégénérescences neurofibrillaires dans un modèle murin de la maladie d’Alzheimer

de Calignon, Alix, Spires-Jones, Tara L., Hyman, Bradley T.

Journal:

médecine/sciences

Year:

2010

Language:

french

File:

PDF, 179 KB

french, 2010

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